abstract：OBJECTIVE:To assess the efficacy and tolerability of weekly oral cyclophosphamide in combination with alternate-day prednisone (CP) as salvage therapy for patients with relapsed multiple myeloma (MM) after autologous stem cell transplantation (ASCT). PATIENTS AND METHODS:We retrospectively reviewed the medical records...

journal_title：Mayo Clinic proceedings

authors： Trieu Y,Trudel S,Pond GR,Mikhael J,Jaksic W,Reece DE,Chen CI,Stewart AK

更新日期：2005-12-01 00:00:00

abstract：:Severe hypocalcemia may require prompt intervention to avoid life-threatening consequences. We report a case in which a 78-year-old man had a critically low serum calcium level measured with use of standard colorimetric assay after gadodiamide administration during magnetic resonance angiography. Reanalysis of the sam...

journal_title：Mayo Clinic proceedings

authors： Williams SF,Meek SE,Moraghan TJ

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy with bronchoalveolar lavage (BAL) and transbronchial biopsy in patients with febrile neutropenia and pulmonary infiltrates. PATIENTS AND METHODS:We retrospectively reviewed the medical records of all patients with...

journal_title：Mayo Clinic proceedings

authors： Peikert T,Rana S,Edell ES

更新日期：2005-11-01 00:00:00

abstract：:Cirrhosis and its disease-related complications are the 12th leading cause of mortality among U.S. adults and are the 5th leading cause of death for individuals aged 45 to 54 years. Hospitalization costs for disease-related complications are estimated at 18,000 dollars per episode of care, and 10% of admitted patients...

journal_title：Mayo Clinic proceedings

authors： Talwalkar JA,Kamath PS

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:To assess the potential electromagnetic interference (EMI) effects that new or current-generation cellular telephones have on medical devices. MATERIAL AND METHODS:For this study, performed at the Mayo Clinic in Rochester, Minn, between March 9, 2004, and April 24, 2004, we tested 16 different medical device...

journal_title：Mayo Clinic proceedings

authors： Tri JL,Severson RP,Firl AR,Hayes DL,Abenstein JP

更新日期：2005-10-01 00:00:00

abstract：:Since first described In 1961, methicillin-resistant Staphylococcus aureus (MRSA) has become a common nosocomial pathogen. Substantial increases in MRSA infections among nonhospitalized patients are being reported. Methicillin-resistant S. aureus is the most common isolate from skin and soft tissue infections in selec...

journal_title：Mayo Clinic proceedings

authors： Kowalski TJ,Berbari EF,Osmon DR

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To Investigate the frequency of valvular heart disease in patients taking pergolide. PATIENTS AND METHODS:The medical records of patients seen at the Mayo Clinic in Jacksonville, Fla, between 1998 and 2003 were searched electronically for the word pergolide and the presence of a 2-dimensional echocardiogram....

journal_title：Mayo Clinic proceedings

authors： Waller EA,Kaplan J,Heckman MG

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:To estimate the magnitude of association between intraoperative hyperglycemia and perioperative outcomes in patients who underwent cardiac surgery. PATIENTS AND METHODS:We conducted a retrospective observational study of consecutive adult patients who underwent cardiac surgery between June 10, 2002, and Augu...

journal_title：Mayo Clinic proceedings

authors： Gandhi GY,Nuttall GA,Abel MD,Mullany CJ,Schaff HV,Williams BA,Schrader LM,Rizza RA,McMahon MM

更新日期：2005-07-01 00:00:00

abstract：:Unintentional intra-arterial injection of medication, either iatrogenic or self-administered, is a source of considerable morbidity. Normal vascular anatomical proximity, aberrant vasculature, procedurally difficult situations, and medical personnel error all contribute to unintentional cannulation of arteries in an a...

journal_title：Mayo Clinic proceedings

authors： Sen S,Chini EN,Brown MJ

更新日期：2005-06-01 00:00:00

abstract：:Arterial calcification in the coronary arteries frequently indicates concomitant atherosclerotic plaque but can be present in the medial layers with no evidence of plaque. Calcification of the medial layer of arteries is seen most often in the peripheral arteries but also is widely recognized In the coronary arteries....

journal_title：Mayo Clinic proceedings

authors： Qiao JH,Doherty TM,Fishbein MC,Salusky IB,Luthringer DL,Fitzpatrick LA,Shah PK,Rajavashisth TB

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of laparoscopy in the diagnosis of intra-abdominal lymphoma. PATIENTS AND METHODS:The medical records of patients with suspected primary or recurrent lymphoma who underwent laparoscopy between March 1991 and March 2003 were reviewed. Demographic, clinical, operative, and pathologic dat...

journal_title：Mayo Clinic proceedings

authors： Asoglu O,Porter L,Donohue JH,Cha SS

更新日期：2005-05-01 00:00:00

abstract：:In May 2004, representatives from local, state, and national public and private organizations met in Rochester, Minn, for the Action on Obesity Summit hosted by Mayo Clinic. The overall goal of this summit was to identify creative and effective strategies to Increase the US population's physical activity and improve n...

journal_title：Mayo Clinic proceedings

authors： Smith AM,Lopez-Jimenez F,McMahon MM,Thomas RJ,Wellik MA,Jensen MD,Hensrud DD

更新日期：2005-04-01 00:00:00

abstract：:Osteoporosis is a skeletal disorder characterized by compromised bone strength and increased risk of fracture. Properties related to bone strength include rate of bone turnover, bone mineral density, geometry, microarchitecture, and mean degree of mineralization. These properties (with or without bone density) are som...

journal_title：Mayo Clinic proceedings

authors： Epstein S

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To assess resource utilization and outcome in gravely ill patients admitted to an intensive care unit (ICU) and the potential association with health care workers' and family members' expectations. PATIENTS AND METHODS:We retrospectively evaluated ICU patients with a predicted in-hospital mortality rate of 9...

journal_title：Mayo Clinic proceedings

authors： Berge KH,Maiers DR,Schreiner DP,Jewell SM,Bechtle PS,Schroeder DR,Stevens SR,Lanier WL

更新日期：2005-02-01 00:00:00

abstract：:Millions of cigarette smokers require surgery each year. Those who quit smoking may reduce their risk of respiratory, cardiovascular, and wound-related complications. Scheduling of surgery may present a unique opportunity to help smokers quit permanently. Primary care providers can play an important role in helping th...

journal_title：Mayo Clinic proceedings

authors： Warner DO

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the frequency and pattern of complementary and alternative medicine (CAM) use in patients referred to a fibromyalgia treatment program at a tertiary care center. PATIENTS AND METHODS:Patients referred to the Mayo Fibromyalgia Treatment Program between February 2003 and July 2003 were invited on t...

journal_title：Mayo Clinic proceedings

authors： Wahner-Roedler DL,Elkin PL,Vincent A,Thompson JM,Oh TH,Loehrer LL,Mandrekar JN,Bauer BA

更新日期：2005-01-01 00:00:00

abstract：:Physicians must be able to recognize stroke caused by a mendelian or mitochondrial disorder. Some genetic disorders such as sickle cell anemia and Fabry disease have proven disease-specific treatments, whereas others have no effective treatment, including cerebral autosomal dominant arteriopathy with subcortical infar...

journal_title：Mayo Clinic proceedings

authors： Meschia JF,Brott TG,Brown RD Jr

更新日期：2005-01-01 00:00:00

abstract：:Traditional treatments for men with localized prostate cancer have included both surgical removal and radiation therapy, with their potential adverse effects on patient quality of life. Thus, there has been increasing interest in the development of minimally invasive procedures that use various technologies to deliver...

journal_title：Mayo Clinic proceedings

authors： Gillett MD,Gettman MT,Zincke H,Blute ML

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To determine the percentage of metastatic and unexpected residual lung cancer at autopsy in patients considered for curative resection of non-small cell lung cancer during a time when computed tomography was available as a preoperative staging tool. MATERIAL AND METHODS:Clinical data and surgical and autopsy...

journal_title：Mayo Clinic proceedings

authors： Finke NM,Aubry MC,Tazelaar HD,Aughenbaugh GL,Lohse CM,Pankratz VS,Deschamps C

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:To investigate presenting signs and symptoms of ovarian cancer and stage of tumor in a community cohort of women with the diagnosis of ovarian cancer. PATIENTS AND METHODS:We reviewed retrospectively the medical records of all women who sought primary and specialty care in Olmsted County, Minnesota, between ...

journal_title：Mayo Clinic proceedings

authors： Yawn BP,Barrette BA,Wollan PC

更新日期：2004-10-01 00:00:00

abstract：:The development of advanced laparoscopic techniques and robot-assisted technology has resulted in several new surgical approaches for treating organ-confined prostate cancer. Outcomes with these new or minimally Invasive techniques should be assessed carefully to ensure that they are similar to or surpass patients' on...

journal_title：Mayo Clinic proceedings

authors： Humphreys MR,Gettman MT,Chow GK,Zincke H,Blute ML

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:To present the results of a quality-of-life (QOL) assessment performed with the current version of the Lung Cancer Symptom Scale (LCSS) questionnaire in a large single-institutional data set of 650 patients with lung cancer. PATIENTS AND METHODS:The study group included 650 patients with pathologically confi...

journal_title：Mayo Clinic proceedings

authors： Svobodník A,Yang P,Novotny PJ,Bass E,Garces YI,Jett JR,Bonner JA,Sloan JA

更新日期：2004-08-01 00:00:00

abstract：:Restless legs syndrome (RLS) is a common disorder with a prevalence of 5% to 15%. Primary care physicians must become familiar with management of this disorder. This algorithm for the management of RLS was written by members of the Medical Advisory Board of the Restless Legs Syndrome Foundation and is based on scienti...

journal_title：Mayo Clinic proceedings

authors： Silber MH,Ehrenberg BL,Allen RP,Buchfuhrer MJ,Earley CJ,Hening WA,Rye DB,Medical Advisory Board of the Restless Legs Syndrome Foundation.

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To study differences in treatment outcomes between patients with chronic noncancer pain taking vs those not taking maintenance opioids at admission to a pain rehabilitation program. PATIENTS AND METHODS:A nonrandomized 2-group prepost design was used to compare 356 patients admitted to the Mayo Comprehensive...

journal_title：Mayo Clinic proceedings

authors： Rome JD,Townsend CO,Bruce BK,Sletten CD,Luedtke CA,Hodgson JE

更新日期：2004-06-01 00:00:00

abstract：:A 70-year-old woman was admitted to the hospital with chest discomfort after quarreling with her neighbors. Electrocardiography revealed ST-segment elevation in leads I, II, III, aVL, aVF, and V2 through V6. Coronary angiography demonstrated normal arteries, but left ventriculography showed apical akinesis and basal h...

journal_title：Mayo Clinic proceedings

authors： Akashi YJ,Tejima T,Sakurada H,Matsuda H,Suzuki K,Kawasaki K,Tsuchiya K,Hashimoto N,Musha H,Sakakibara M,Nakazawa K,Miyake F

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of treatment with fluticasone propionate vs placebo on bone, hypothalamic-pituitary-adrenal (HPA) axis function, and the eyes in patients with asthma. PATIENTS AND METHODS:This randomized, double-blind, placebo-controlled study of 160 patients with asthma who had minimal previous expo...

journal_title：Mayo Clinic proceedings

authors： Kemp JP,Osur S,Shrewsbury SB,Herje NE,Duke SP,Harding SM,Faulkner K,Crim CC

更新日期：2004-04-01 00:00:00

abstract：:The use of pacemakers and implantable cardioverter-defibrillators continues to increase for the management of cardiac dysrhythmias and, more recently, heart failure. Long-term complications associated with their use include infection, lead failure, and spurious shocks. Although the risk of infection with intracardiac ...

journal_title：Mayo Clinic proceedings

authors： Cook RJ,Orszulak TA,Nkomo VT,Shuford JA,Edwards WD,Ryu JH

更新日期：2004-04-01 00:00:00

abstract：:The Human Genome Project has resulted in a new era in the field of pharmacogenetics in which researchers are rapidly discovering new genetic variation, which may help to explain interindividual variability in drug efficacy and toxicity. Pharmacogenetics is the study of the role of genetic inheritance in individual var...

journal_title：Mayo Clinic proceedings

authors： Goetz MP,Ames MM,Weinshilboum RM

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:To determine the long-term outcome of patients presenting with synchronous lymphoma and severe liver dysfunction and to describe the outcome of patients treated with initial mechlorethamine-based therapy used as a bridge to more conventional chemotherapy. PATIENTS AND METHODS:We reviewed the clinical course...

journal_title：Mayo Clinic proceedings

authors： Ghobrial IM,Wolf RC,Pereira DL,Fonseca R,White WL,Colgan JP,Habermann TM,Inwards DJ,Markovic SN,Ansell SM,Micallef IN,Porrata LF,Witzig TE

更新日期：2004-02-01 00:00:00

abstract：:Primary infection with Pneumocystis carinii usually occurs early in life, and young infants receiving prolonged treatment with high-dose corticosteroids may be at risk for the development of symptomatic disease. Prophylaxis with trimethoprim-sulfamethoxazole is safe and effective and should be considered for such infa...

journal_title：Mayo Clinic proceedings

authors： Aviles R,Boyce TG,Thompson DM

更新日期：2004-02-01 00:00:00

abstract：:Risk stratification and risk-benefit ratios are extremely important in guiding patient-physician interactions as well as patient and family counseling. Risks associated with percutaneous transluminal coronary angioplasty are (1) compromise of the vessel lumen or vessel integrity, (2) unsuccessful procedure, and (3) re...

journal_title：Mayo Clinic proceedings

authors： Holmes DR Jr

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To determine whether a diet of high saturated fat and avoidance of starch (HSF-SA) results in weight loss without adverse effects on serum lipids in obese nondiabetic patients. PATIENTS AND METHODS:Twenty-three patients with atherosclerotic cardiovascular disease participated in a prospective 6-week trial at...

journal_title：Mayo Clinic proceedings

authors： Hays JH,DiSabatino A,Gorman RT,Vincent S,Stillabower ME

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and tolerability of sumatriptan, 50-mg and 100-mg tablets, compared with placebo for treatment of migraine at the first sign of pain. PATIENTS AND METHODS:Two identical multicenter randomized, double-blind, placebo-controlled, single-attack studies were conducted from May through Nov...

journal_title：Mayo Clinic proceedings

authors： Winner P,Mannix LK,Putnam DG,McNeal S,Kwong J,O'Quinn S,Richardson MS

更新日期：2003-10-01 00:00:00

abstract：:We treated a patient who developed transient multifocal encephalopathy with extrapyramidal symptoms (oromandibular dystonia, oculogyric crisis, and limb dystonia) in temporal proximity to ondansetron administration on emergence from general anesthesia. No other medications known to cause extrapyramidal reactions were ...

journal_title：Mayo Clinic proceedings

authors： Ritter MJ,Goodman BP,Sprung J,Wijdicks EF

更新日期：2003-09-01 00:00:00

abstract：:Tobacco use is a global pandemic. The most common pharmacological treatments of tobacco use and dependence include nicotine replacement therapy and nonnicotine medications. Bupropion sustained release (SR) is the only first-line nonnicotine medication recommended by the US Public Health Service Clinical Practice Guide...

journal_title：Mayo Clinic proceedings

authors： Hays JT,Ebbert JO

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:To describe 3 patients who presented with chest pain and intermittent Q waves on the electrocardiogram (ECG) and were subsequently found to have latent preexcitation. PATIENTS AND METHODS:During a span of 8 years, 3 patients were evaluated because of atypical chest pain and pathologic Q waves in the inferior...

journal_title：Mayo Clinic proceedings

authors： Letts DP,Constantine JC,Littmann L

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the overall risk of breast cancer and breast cancer characteristics in women given supradiaphragmatic radiation therapy for Hodgkin lymphoma. PATIENTS AND METHODS:Medical records of 653 female patients who received supradiaphragmatic radiation therapy for Hodgkin lymphoma at the Mayo Clinic in Ro...

journal_title：Mayo Clinic proceedings

authors： Wahner-Roedler DL,Nelson DF,Croghan IT,Achenbach SJ,Crowson CS,Hartmann LC,O'Fallon WM

更新日期：2003-06-01 00:00:00

abstract：:Considerable advances in the diagnosis and treatment of migraine headache have occurred during the past decade, but treatment options for acute migraine attacks have expanded at a faster rate than those for prophylaxis. We describe a patient whose migraine headaches responded dramatically to sustained-release niacin a...

journal_title：Mayo Clinic proceedings

authors： Velling DA,Dodick DW,Muir JJ

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To evaluate, in this before-and-after study, the results of 5 strategies for improving attendance at medical grand rounds at a tertiary care academic medical center. METHODS:The strategies included (1) using electronic card readers to improve understanding of attendance patterns, (2) conducting yearly needs ...

journal_title：Mayo Clinic proceedings

authors： Mueller PS,Litin SC,Sowden ML,Habermann TM,LaRusso NF

更新日期：2003-05-01 00:00:00

abstract：:Clopidogrel bisulfate, a widely used inhibitor of platelet aggregation, is considered at least as safe as aspirin. We describe a patient who developed a systemic inflammatory response syndrome consisting of high fever, tachycardia, cellulitis-like rash, impaired liver function, and mild leukopenia after receiving clop...

journal_title：Mayo Clinic proceedings

authors： Wolf I,Mouallem M,Rath S,Farfel Z

更新日期：2003-05-01 00:00:00